{"id":1939,"date":"2018-11-26T05:34:34","date_gmt":"2018-11-26T05:34:34","guid":{"rendered":"https:\/\/ncrfrontlinenews.com\/?p=1939"},"modified":"2018-11-26T05:34:34","modified_gmt":"2018-11-26T05:34:34","slug":"air-pollution-exposure-linked-to-breast-cancer-study","status":"publish","type":"post","link":"https:\/\/ncrfrontlinenews.com\/?p=1939","title":{"rendered":"Air pollution exposure linked to breast cancer: Study"},"content":{"rendered":"

London,\u00a0\u00a0<\/strong>Women working near busy roads are at high risk of developing breast cancer, due to traffic-related air pollution, researchers have warned.<\/p>\n

The team, from University of Stirling in Scotland, analysed the case of a woman who developed breast cancer after spending 20 years working as a border guard at the busiest commercial border crossing in North America.<\/p>\n

The woman was one of, at least, five other border guards who developed breast cancer within 30 months of each other and, at another nearby crossing, a cluster of seven other cases was noted.<\/p>\n

According to Michael Gilbertson, the findings “infer a causal relationship” between breast cancer and very high exposures to traffic-related air pollution containing mammary carcinogens. A link between nightshift work and cancer was also identified.<\/p>\n

“This new research indicates the role of traffic-related air pollution in contributing to the increasing incidence of breast cancer in the general population,” Gilbertson said.<\/p>\n

The group of women all developed a cancer believed to have been caused by exhaust fumes in what researchers have branded a ‘new occupational disease’.<\/p>\n

There is a one in 10,000 chance the cases were a coincidence, the study published in the journal New Solutions said, because the cancers were all so similar and close together.<\/p>\n

A review of previous research confirmed that BRCA1 and BRCA2 genes — which try to stop tumours growing — can be “silenced” by exposures to dioxins and polycyclic aromatic hydrocarbons – both found in exhaust fumes.<\/p>\n

BRCA2 gets rapidly degraded in the presence of aldehydes – also components of exhaust fumes.<\/p>\n

“There is much more research to be undertaken,” Gilbertson said. “But we now have plausible mechanisms for inferring how the BRCA1\/2 tumour suppressors in this highly-exposed border guard became dysfunctional and likely contributed to the ongoing epidemic of sporadic, early onset, premenopausal breast cancer among her colleagues.<\/p>\n

“With this new knowledge, industry and government can plan for new designs for industrial and commercial facilities to cut down on the occupational exposures to traffic-related air pollution,” Gilbertson said.<\/p>\n","protected":false},"excerpt":{"rendered":"

London,\u00a0\u00a0Women working near busy roads are at high risk of developing breast cancer, due to traffic-related air pollution, researchers have warned. The team, from University of Stirling in Scotland, analysed the case of a woman who developed breast cancer after spending 20 years working as a border guard at the busiest commercial border crossing in […]<\/p>\n","protected":false},"author":2,"featured_media":1940,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":{"0":"post-1939","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health"},"_links":{"self":[{"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=\/wp\/v2\/posts\/1939","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1939"}],"version-history":[{"count":1,"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=\/wp\/v2\/posts\/1939\/revisions"}],"predecessor-version":[{"id":1941,"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=\/wp\/v2\/posts\/1939\/revisions\/1941"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=\/wp\/v2\/media\/1940"}],"wp:attachment":[{"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1939"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1939"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ncrfrontlinenews.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1939"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}